<p>Trevor Penning is out, heightening the Saints' protection concerns and potentially increasing SF's edge pressure opportunities.</p><p>SF's plan could target the right side of the Saints' line and force hurried throws, aiding Jones's efficiency in a difficult road setting.</p>

Penning’s Week 2 availability drives NO’s protection plan and affects Carr’s pocket timing versus SF. Backup tackles must absorb edge pressure, influencing Saints’ pass-run balance and fantasy targets for receivers and backs if the blind side is compromised.

Penning sat Week 1, leaving Banks with a longer baptism and a thinner line. His return could shift Banks into more run-blocking reps and help stabilize the Saints’ left side. Penning’s absence highlighted Banks’ resilience and readiness to contribute to a more cohesive unit as the season progresses.

Trevor Penning sidelined with a toe injury, leaving Saints' left guard depth tested. His absence may impact interior protection and run-blocking schemes, with fantasy angles focusing on how the Saints adapt their line and the potential ripple effects on the run game and short-area passes.

Trevor Penning out with toe issue; Saints' left guard depth tested; potential run-protection implications against the Cardinals.